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Alistipes onderdonkii

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Sources cited
1 project report and 1 cross-project digest, listed in the margin
Linked from
3 pages1 topic

Alistipes onderdonkii is a gut commensal bacterium that the corpus describes as having substantial intraspecific metabolic diversity 1. The assigned evidence records no external identifier, such as an NCBI taxid.

Metabolic ecotypes

The pathway capability and dependency analysis grouped binary GapMind pathway profiles by hierarchical clustering with Jaccard distance. It covered 225 species that had sufficient genome diversity, meaning 50+ genomes and 3+ variable pathways. In that analysis, A. onderdonkii (8 ecotypes) and Barnesiella intestinihominis (8 ecotypes) were the species with the most inferred metabolic ecotypes. Both are gut commensals with substantial intraspecific metabolic diversity 1.

The central discoveries digest repeats this pathway_capability_dependency finding rather than corroborating it independently. Its entry lists Alistipes onderdonkii (8) and Barnesiella intestinihominis (8) as the top ecotyped species 2.

Caveat: the ecotype count of 8 is a clustering inference, not a set of directly observed populations. The source calls its hierarchical clustering with a fixed 50% distance threshold a simplification and states that different distance thresholds would yield different ecotype counts. It also says the median of 4 ecotypes per species should be read as an order-of-magnitude estimate. The figure of 8 for A. onderdonkii therefore depends on the threshold that was chosen. For broader discussion, see ecotype-clustering-validity 1.

Sources cited

  1. Metabolic Capability vs Dependencypathway_capability_dependency · cited 4× · primary source
  2. Discoveries Logdiscoveries · cited 1× · cross-project digest