Identity
Canonical name: Molybdenum 1
Known alias: Mo 1
Stable external identifier: No stable external identifier was reported in the source document. 1
Evidence across projects
Molybdenum was the most independent metal in the 13-metal DvH dataset, showing weaker similarity to the other metals than the remaining metals in that dataset. 1 This finding contributes to the chemistry-dependent magnitude layer of metal-cross-resistance, in which cross-resistance is broadly positive but varies in strength among metal pairs. 1
The Pan-Bacterial Metal Fitness Atlas refines this interpretation by showing that molybdenum-associated fitness genes were strongly core-enriched: 302 important genes had a core fraction of 0.950, delta +0.148, OR=5.32, and p=1.3e-14. 2 Molybdenum was also among the essential metals whose tolerance genes showed stronger core enrichment than toxic-metal tolerance genes; the essential-metal mean core-fraction delta was +0.148 versus +0.081 for toxic metals (U=39, p=0.015). 2 This supports a distinction between conserved cellular functions vulnerable to metal stress and specialized accessory resistance mechanisms, rather than implying that molybdenum responses are uniformly shared across metals. 2
The Metal-Specific vs General Stress Genes refines this core-enrichment picture by classifying 185 of 306 molybdenum-important gene records (60.5%) as metal-specific—significant under metal stress but with a sick rate below 5% across non-metal experiments. 3 Thus, strong conservation and substantial condition specificity coexist for molybdenum-associated genes; this result is based on the subset with usable fitness-matrix identifiers. 3
The result was based on gene-level fitness responses analyzed across diverse bacteria and is part of the cross-resistance structure summarized in Gene-Resolution Metal Cross-Resistance Across Diverse Bacteria. 1
Related pages
- metal-cross-resistance — synthesis of conserved and chemistry-dependent metal cross-resistance.
- cofitness-network-architecture — gene-level fitness correlations across metal conditions.
- condition-specific-fitness — condition-linked gene importance measured across metal experiments.
- Gene-Resolution Metal Cross-Resistance Across Diverse Bacteria — source-project summary.
- Pan-Bacterial Metal Fitness Atlas — cross-species metal fitness atlas.
- Metal-Specific vs General Stress Genes — metal-specific versus general-stress gene classification.