Identity
Canonical name: Lysine. 1
Known aliases: No aliases were reported in this document. 1
Stable external identifier: No stable external identifier was reported in this document. 1
Evidence from FW300-N2E3
Lysine emerged in the Web of Microbes exometabolome of pseudomonas-fw300-n2e3 and was among the 13 metabolites with complete gapmind pathway predictions. 1
Lysine also showed growth in the Fitness Browser experiment used for the cross-database comparison, making it part of the 13/13 set in which complete GapMind predictions agreed with Fitness Browser growth measurements. 1
In bacdive, lysine utilization was observed in 0 of 3 strains, reported as 0+/3-, with moderate confidence. 1
The report treats the lysine production-versus-utilization result as a consistent negative BacDive observation but emphasizes that the sample size of 3 strains is too small for a strong species-level conclusion. 1
The lysine result therefore distinguishes production from utilization: FW300-N2E3 released or accumulated lysine in WoM and showed growth in a matched Fitness Browser condition, whereas the available species-level BacDive records did not show lysine utilization. 1
Pathway Capability and Accessory Contribution
The newer pathway-capability analysis refines the earlier complete GapMind interpretation by showing that lysine biosynthesis had all-gene completeness of 0.804, core-only completeness of 0.664, and an exact accessory-dependent gap of 0.140 across the analyzed genomes. 2 This supports the interpretation that lysine biosynthetic capacity can depend partly on genes outside the universally conserved core, while not itself demonstrating lysine exchange between organisms. 2
Related Pages
- Metabolic Consistency of Pseudomonas FW300-N2E3 Across Four KBase Data Lakehouse Databases — source report for the cross-database lysine evidence. 1
- Metabolic Capability vs Dependency — source report for lysine pathway completeness and accessory-gene evidence. 2
- multi-omics-integration — lysine is part of the report’s integration of exometabolomics, fitness, phenotype, and pathway data. 1
- condition-specific-fitness — the lysine result contributes to condition-specific Fitness Browser interpretation. 1
- metabolic-model-gapfilling — complete GapMind prediction for lysine was concordant with Fitness Browser growth. 1
- gene-function-acquisition-depth — lysine biosynthetic completeness differed between all-gene and core-only analyses by 0.140. 2
- cross-tenant-data-bridging — the result required matching lysine across multiple KBase Data Lakehouse databases. 1