Identity
Canonical name: Klebsiella michiganensis 1
Known alias: Koxy 1
Stable external identifier: Not specified in this study 1
Key facts across studies
Klebsiella michiganensis had the highest reported annotation-gap resolution rate in the study, with 5 of 7 gapfilled reaction-organism pairs resolved, corresponding to exactly 71.4%. 1
The study evaluated 14 organisms and found that resolution rates ranged from 20% in Bacteroides thetaiotaomicron to 71% in K. michiganensis. 1
The result places K. michiganensis above the other reported organisms: Marinobacter resolved 8 of 12 pairs (66.7%), Azospirillum brasilense resolved 13 of 21 (61.9%), Herbaspirillum seropedicae resolved 10 of 17 (58.8%), Escherichia coli Keio resolved 4 of 7 (57.1%), and Bacteroides thetaiotaomicron resolved 3 of 15 (20.0%). 1
The report associated higher resolution with better-annotated reference genomes and stronger Fitness Browser coverage, while noting that this association does not by itself establish causation. 1
A separate metabolic capability–dependency analysis identified K. michiganensis among the organisms with the highest reported proportions of latent capabilities—complete pathways with low measured fitness dependence—refining the annotation-gap result by showing that strong annotation resolution does not imply that every encoded pathway is an active dependency. 2
Related pages
This organism is discussed in the study summaries Annotation-Gap Discovery via Phenotype-Fitness-Pangenome-Gapfilling Integration and Metabolic Capability vs Metabolic Dependency. 1,2
Its resolution result contributes to metabolic-model-gapfilling, which synthesizes evidence about resolving candidate genes for gapfilled reactions. 1
Its resolution result also relates to pangenome-integration through the use of pangenome conservation and to condition-specific-fitness through Fitness Browser carbon-source phenotypes. 1