PROTECT Gold (stored at ~/protect/gold/) is a named data collection of 23 tables (30.5M rows). It covers an isolate catalog, inhibition assays, carbon utilization, growth kinetics, patient metagenomics and pairwise interactions. 1
Data-quality caveat
Two PROTECT Gold tables, fact_pairwise_interaction and fact_carbon_utilization, contain identical values (correlation = 1.0, mean difference = 0.0). This was flagged in the cf_formulation_design project. The endpoint optical-density (OD) data therefore does not capture co-culture metabolic interactions. Only the RFU-based (relative fluorescence unit) competition assay provides pairwise interaction effects. Analyses that need pairwise effects should not treat fact_pairwise_interaction as an independent measurement. 2
Related Pages
- Rational Design of Protective Microbiome Formulations for Competitive Exclusion of *Pseudomonas aeruginosa* in Cystic Fibrosis Airways — the project that used PROTECT Gold
- pitfalls — the central record of the pairwise-interaction table duplication